Select the keyword or phrase that will best complete each sentence. A Claisen reaction is a nucleophilic ____________ in which an enolate

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Select the keyword or phrase that will best complete each sentence. A Claisen reaction is a nucleophilic ____________ in which an enolate is the nucleophile.

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Nguyệt Ánh 5 years 2021-08-23T03:13:31+00:00 1 Answers 11 views 0

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  1. minhkhue
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    2021-08-23T03:14:54+00:00
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    Answer:

    Substitution.

    Explanation:

    Claisen reaction was first published in 1887 by a prominent German chemist known as Rainer Ludwig Claisen.

    A Claisen reaction is a nucleophilic substitution in which an enolate is the nucleophile. It’s typically a reaction of two molecules of an ester to form a β-keto ester, in the presence of an alkoxide base. Thus, a Claisen reaction is simply a characteristic condensation reaction of esters through a nucleophilic carbonyl substitution with an enolate such as a ketone enolate or an ester enolate.

    Furthermore, a Claisen reaction results in the formation of a carbon-carbon bond in the presence of a strong base to yield a β-keto ester.

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Giải phương trình 1 ẩn: x + 2 - 2(x + 1) = -x . Hỏi x = ? ( )