What happen if your Adrenal Glands become overprotective of underproductive?

What happen if your Adrenal Glands become overprotective of underproductive?

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  1. What happen if your Adrenal Glands become overprotective of underproductive?

    Answer: if your adrenals becomes overproductive it will lead to a health issue known as CUSHING’S SYNDROME while when they become underproductive it will lead to a health condition known as ADDISON’S DISEASE.

    Explanation:

    The adrenal glands are divided into two embryologically and functionally distinct parts: the adrenal cortex and adrenal medulla.

    The adrenal cortex is part of the hypothalamic – pituitary – adrenal endocrine system. Morphologically, the adult adrenal cortex consists of three layers which include:

    –> The outer thin layer: this is also called zona glomerulosa. It secrets only aldosterone.

    –> The inner two layers: these comprises of the zona fasciculata and zona reticularis. They both form a functional unit and secrete most of the adrenocortical hormones.

    The adrenal medulla is the inner part of the adrenal gland which secrets the adrenaline and noradrenaline hormones.thry take part in sympathetic nervous system.

    When the adrenal glands become a OVERPRODUCTIVE, the adrenal cortex is highly affected. This may occur due to hyperstimulation of the adrenal gland by adrenocorticotrophic hormone,either from the pituitary gland or from an ectopic source or due to largely autonomous secretion by an adrenal tumor such as an adenoma or carcinoma. The increased endogenous cortisol production leads to a disorder known as CUSHING’S SYNDROME. The clinical and metabolic features include obesity, hyperglycaemia and hypertension.

    Also when the adrenal glands become UNDERPRODUCTIVE, a health condition known as ADDISON’S DISEASE may occur. This is cause any the bilateral destruction of all zones of the adrenal cortex, usually as the result of an autoimmune process or mycotic infections. The resulting decrease in cortisol production may lead to clinical features such as hypotension, hypoglycemia, nausea and vomiting.

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