What enzyme catalyses the reaction of PRPP transfer to hypoxanthine with formation of IMP?

Question

What enzyme catalyses the reaction of PRPP transfer to hypoxanthine with
formation of IMP?

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Thu Cúc 6 months 2021-07-11T07:53:37+00:00 1 Answers 12 views 0

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    2021-07-11T07:54:58+00:00

    Answer:

    HPRT

    Explanation:

    HPRT catalyzes the salvage reactions of hypoxanthine and guanine with PRPP to form IMP and GMP

    The formation of GMP from IMP requires oxidation at C-2 of the purine ring, followed by a glutamine-dependent amidotransferase reaction that replaces the oxygen on C-2 with an amino group to yield 2-amino,6-oxy purine nucleoside monophosphate, or as this compound is commonly known, guanosine monophosphate.

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Giải phương trình 1 ẩn: x + 2 - 2(x + 1) = -x . Hỏi x = ? ( )